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Garen's regeneration greatly increases if he can avoid receiving damage for several seconds.
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Judgment deals maximum damage when only hitting a single target. For effective trading, try to position such that only the enemy champion is hit.
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Garen is only constrained by cooldowns, making items such as Black Cleaver very effective for him.
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Stack armor items to lower the large amount of physical damage that Garen deals out.
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Try to run away from Garen as your health gets lower, as he can execute you quickly with Demacian Justice.
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Be careful about attacking Garen in brush. It often will lead to taking full damage from Judgment.
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Judgment deals maximum damage when only hitting a single target. If getting out of its radius isn't possible, move through allied minions to reduce damage taken.