Tips for playing as the champion Vladimir
◊ Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
◊ Cast Hemoplague where it will afflict the most units.
◊ Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Tips for playing against the champion Vladimir
◊ Try to take Vladimir down before Hemoplague detonates, as it will heal him for each afflicted enemy Champion.
◊ Making Vladimir use Sanguine Pool at the start of a fight will maximize the Health cost of the ability to him.
◊ Items that counter Health stacking, such as Liandry's Torment and Blade of the Ruined King, are very effective against Vladimir.